Ingabe ufuna ukushisa amafutha engeziwe emzimbeni wakho?
Ama-SARM (ama-selective androgen receptor modulators) ayizithasiselo zokwakha imisipha ezifunwa kakhulu esezidume kakhulu ngenxa yekhono labo lokusiza abantu ukuthi bafinyelele imigomo yabo yokulahlekelwa isisindo. Lezi zithako ezinamandla zithembisa imiphumela esheshayo enemiphumela engemihle emincane ukuze uqiniseke ukuthi uhlala unempilo ngenkathi uzuza umzimba owufisayo.
Ngakho-ke, uma usulungele ukushisa amanoni anzima futhi ungene esimeni ngokushesha, qhubeka ufunda njengoba sihlola ama-SARM angcono kakhulu okulahlekelwa kwamafutha.
I-Cardarine (i-GW-501516)
I-Cardarine, owaziwa nangokuthi i-GW-501516, ngokushesha iba enye ye-SARM ethandwa kakhulu yokulahlekelwa kwamafutha. Le nhlanganisela isiza abasebenzisi ukuthi bashise amafutha anenkani futhi behlise isisindo somzimba sisonke ngokuvuselela ukumuncwa kwe-glucose emisipha kanye nokukhuthaza ukushiswa kwamafutha.
I-GW-501516 isebenza ngokuhlela kabusha umzimba ukusebenzisa ama-fatty acids esikhundleni samacarbohydrate njengomthombo wamandla oyinhloko, okuwuvumela ukuba ushise amafutha amaningi kunokuvamile. Lokhu kuhumushela ekuncipheni kwamazinga wamafutha omzimba kanye nesisindo, kungakhathaliseki ukuthi uyakushintsha yini ukudla kwakho. Nokho, ucwaningo luye lwasikisela ukuthi labo abadla kangcono baba nemiphumela engcono kakhulu.
Le SARM ingasiza futhi abasubathi bokukhuthazela abanekhono elithuthukisiwe le-aerobic, elizuzisa kakhulu ngesikhathi sokusebenza okugxile ekuzilolongeni kwenhliziyo njengokugijima noma ukubhukuda; kulabo abafuna ukusebenzisa i-Cardarine ukuze bachithe amafutha engeziwe ngenkathi beqeqeshwa, kuphumelela ikakhulukazi ekuqedeni amafutha agcinwe ezindaweni ezifana nezingalo, isifuba, nokhalo. Uma ucabangela lokhu, i-Cardarine ivela njengesengezo esinamandla esandisa imiphumela yakho kunoma yiluphi uhlobo lokuqeqeshwa, okukuvumela ukuba ufinyelele imigomo yakho yokufaneleka ngokushesha nangempumelelo kunanini ngaphambili.
Enye yezinzuzo ezinkulu zeCardarine ukuthi ingasiza noma ubani ukuba alahlekelwe amafutha nesisindo. Kungakhathaliseki ukuthi ukhuluphele ngokweqile, usuvele unciphile, noma usayizi ojwayelekile-i-Cardarine ingakusiza ulahlekelwe amafutha ngokuphepha. I-GW-501516 isebenza ngendlela ehluke kakhulu uma iqhathaniswa nezishisi zamafutha ezisekelwe kwisikhuthazi. Kungandisa izindlela emzimbeni ezihilelekile ku-fatty acid metabolism. Ngamanye amazwi, i-SARM ilingisa imiphumela yokuzivocavoca ukusiza abagijimi nabakhi bomzimba balahlekelwe amafutha ngokushesha.
The I-Peroxisome Proliferator-Activated Receptor I-agonist ye-beta (PPAR) ibophezela ku-androgen receptor ukuze ikhuthaze ukuguqulwa komsebenzi wofuzo ukuze kubangele ukushintsha endleleni echitha ngayo amandla. Lesi sici seCardarine sivumela abantu ngabanye ukuba bazuze ekhonweni elithuthukisiwe lokusunduza isikhathi eside futhi kanzima uma kuziwa ekukhuthazeleni. Bese ithuthukisa ikhono lomuntu lokuthola inani elithe xaxa ekusebenzeni okujulile, ukuqeqeshwa kwamandla, namaseshini e-cardio njengekhono lokuphindela okunye ukuphindaphinda ngaphandle kokuzwa ukukhathala nokukhathala.
Umthamo onconyiwe we-GW-501516 wamadoda u-10-20mg nsuku zonke emjikelezweni wamaviki ayisishiyagalombili kuya kwayishumi nambili. Ukuthatha i-Cardarine ngokudla futhi okungenani imizuzu engu-30-45 ngaphambi kokuzivocavoca okukhulu kungcono kakhulu. Kwabesifazane, umthamo onconyiwe ngu-5-10mg ngosuku ngokudla futhi okungenani imizuzu engama-30-45 ngaphambi kokuzivocavoca ngomjikelezo wamaviki ayisithupha kuya kwayisishiyagalombili.
I-Stenabolic (SR-9009)
I-Stenabolic (SR-9009) yenzelwe ukwelapha ukukhuluphala kanye nokuphazamiseka kwe-metabolic. Lokhu kwakwakhe kungasheshisa ngempumelelo ukulahleka kwamafutha ngenkathi futhi kusiza ukulondoloza imisipha ethambile. Lokhu kwenzeka ngomthelela wayo omangalisayo kumetabolism ye-glucose namaseli ngemuva kokugcinwa kwamafutha.
Ngaphezu kwalokho, abasebenzisi babike ukusebenza okuthuthukisiwe kwe-aerobic nokukhuthazela, okwenza kube ukukhetha okuhle kulabo abafuna ukushisa amafutha ngenkathi bakha amandla nokubekezela. Ngephrofayili yezokuphepha enhle kakhulu ye-SR-9009, imiphumela emibi emincane, kanye nempumelelo efakazelwe yokushiswa kwamafutha ngokushesha, kulula ukuqonda ukuthi kungani le SARM enamandla iye yanda kakhulu kulabo abafuna imiphumela yokulahlekelwa kwamafutha ngokushesha.
Ngo-2013, ucwaningo olwanyatheliswa ku- Ijenali Yemithi Yemvelo udalule ukuthi i-Stenabolic, i-Rev-erbA (ingxenye ebalulekile yokulawula yewashi le-circadian engaphinda ilawule ukuwohloka kwe-cartilage) isidakamizwa se-agonist, inamandla ayingqayizivele okushintsha iwashi eliwumgogodla lebhayoloji yomzimba. I-Stenabolic kubikwa ukuthi yenza i-Rev-erbA isebenze, ekhulisa ngokuqhubekayo ukukhiqizwa kwe-mitochondria entsha futhi iqede i-mitochondria engasebenzi kahle.
Ungasebenzisa i-Stenabolic solo noma ku-stack ngokusika ama-SARM afana ne-GW-501516 ne-S-4. Lokhu ukusika isitaki izokunikeza amandla amangalisayo okukhulisa ukusebenza kahle kokujima kwakho namaseshini e-cardio. Ilungele ukulahlekelwa amafutha anenkani esiswini kanye ne-visceral, i-Stenabolic ifakazela ukubaluleka kwayo ngokugcina izinga le-metabolism yomzimba ohlangothini oluphakeme, okwenza kube lula kakhulu ukulahlekelwa amafutha nesisindo.
Umthamo onconyiwe we-Stenabolic wamadoda ngu-30mg nsuku zonke, okungcono ngemva kokudla kanye nemizuzu engu-30-40 ngaphambi kokuzivocavoca, emjikelezweni wamaviki ayisishiyagalombili kuya kwayishumi nambili. Kwabesifazane, umthamo wansuku zonke onconyiwe ngu-5-15mg, okungcono ngemva kokudla kanye nemizuzu engama-30-40 ngaphambi kokuzivocavoca, emjikelezweni wamaviki ayisithupha kuya kwayisishiyagalombili.
I-Andarine (i-S-4)
Uma ufuna ukukhipha amafutha futhi uzoncipha, I-Andarine (i-S-4) ingenye ye-SARM engcono kakhulu ongayithatha. Abakhi bomzimba nabathandi bokuqina basebenzise le nhlanganisela enamandla ukusiza ukushisa amafutha ngenkathi igcina imisipha. Ibophezela kuma-receptors afanayo nama-anabolic steroids kodwa ngaphandle kwemiphumela emibi ehambisana nawo.
Akukhona lokho kuphela, i-Andarine ifakazele ukuthi inciphisa ngempumelelo ukuqoqwa kwamafutha e-visceral kubantu okuholela ekubeni nomzimba onethoni. Ukuthatha le SARM kuhle kakhulu kunoma ubani ofuna umkhawulo lapho akha amandla futhi enciphisa amaphesenti abo omzimba ngaphandle kokudela isisindo semisipha.
I-Andarine ibonisa ukusebenza kahle okukhulu ekukhuthazeni i-vascularity nokwandisa ubulukhuni bemisipha ngokubopha nama-androgen receptors amathambo nemisipha. I-S-4 idala i-oxidation yamafutha ngokubopha nama-androgen receptors emafutheni nasezicubu ze-adipose. Ngaphezu kwalokho, i-Andarine iwusizo kakhulu ekuvimbeleni umzimba ekutholeni i-catabolic ngisho nokudla okuphansi.
Umthamo onconywayo we-S-4 wamadoda ungama-50mg nsuku zonke, okungcono ngokudla nangezilinganiso ezimbili ezilinganayo zokuhlukaniswa kuka-25mg kanye ekuseni no-25mg kanye kusihlwa, emjikelezweni wamasonto ayisishiyagalombili kuya kwayishumi nambili.
I-Ostarine (MK-2866)
I-Ostarine (MK-2866) ingenye ye-SARM engcono kakhulu (i-Selective Androgen Receptor Modulators) yokulahlekelwa kwamafutha. Ihlose ama-androgen receptors, okuholela ekukhuleni kwemisipha nokulahlekelwa kwamafutha ngenxa yekhono layo lokubopha ngamangqamuzana amafutha kanye nezicubu zemisipha. Lesi sakhiwo sikwenza kube kuhle kuyo yomibili imijikelezo yokusika kanye ne-bulking.
I-Ostarine ikhuthaza umzimba ukuthi ulondoloze isisindo semisipha, okunciphisa ukufakwa kwamafutha lapho wehlisa ukudla kwakho kwe-caloric ngaphansi kwezinga lokulungisa. Uma usebenzisa i-caloric surplus, ungalindela ukuthi umzimba wakho uguqule lawo makhalori abe yimisipha kunamafutha abe ngokwezinga elimangalisayo.
Ezifundweni, I-Ostarine inyusa isisindo somzimba omncane, ukuncipha kwamafutha futhi kukusize ufinyelele isisindo osifunayo phakathi nesikhathi esifushane uma kuqhathaniswa. Kungasiza futhi abasubathi bakhe amandla namandla, ikwenze kube ukukhetha okuhle kakhulu kulabo abafuna ukungena esimeni esihle noma bathathe ukujima kwabo bakuyise kwelinye izinga.
Ngaphezu kwalokho, i-Ostarine iyimpahla ebalulekile kubasubathi nabakhi bomzimba njengoba ithuthukisa ukuqina kwamathambo abo, ukuqina kwe-tendon, izinga le-collagen metabolism kanye nokuphila kahle kwe-ligament. Lezi yizindaba ezimnandi zabashisekeli bokufaneleka nokwakha umzimba, ikakhulukazi labo abafuna ukunciphisa izikhathi zabo zokululama ngemva kokujima noma ababhekene nokulimala okungapheli. Ukuthuthukisa ukulungisa amathambo ne-tendon kunikeza inqwaba yezinzuzo.
Umthamo onconyiwe we-Ostarine wamadoda ngu-25mg nsuku zonke, okungcono ngokudla kanye nemizuzu ye-30-40 ngaphambi kokuzivocavoca, emjikelezweni wamaviki ayisishiyagalombili kuya kwayishumi nambili. Kwabesifazane, umthamo onconywayo wansuku zonke ngu-12.5mg, okungcono kakhulu ngokudla kanye nemizuzu engama-30-40 ngaphambi kokuzivocavoca, emjikelezweni wamaviki ayisithupha kuya kwayisishiyagalombili.
I-Ligandrol (LGD-4033)
Abantu abaningi baphendukela kuma-SARM ukuze bathole ukusekelwa uma kuziwa ekulahlekelweni kwamafutha. Ezinhlotsheni eziningi ezahlukene ezitholakalayo, enye edume kakhulu yile ILigandrol noma i-LGD-4033.
Nakuba ekuqaleni yathuthukiswa ukwelapha izimo zezokwelapha ezifana ne-muscle atrophy kanye namathambo abuthakathaka, ucwaningo lwakamuva luye lwembula ukuthi i-Ligandrol ingasebenza ngendlela emangalisayo ekusizeni ukunciphisa amafutha omzimba.
Izakhiwo zayo ezingezona ze-hormonal zisho ukuthi abasebenzisi bangalindela ukubona imiphumela ngaphandle kokukhathazeka ngemiphumela emibi ehambisana nezinye izinhlobo zemithi yokulahlekelwa isisindo. Abasebenzisi babike amazinga anyukile wamandla nokugxila okuthuthukisiwe ngokuthatha i-Ligandrol.
I-LGD-4033 iyisinqumo esiphelele sokuthuthukisa impilo yakho nomzimba wakho ngenxa yokuphepha okuqinisekisiwe, njengoba kuboniswe ezifundweni eziningi. Iphephile futhi isebenza kahle kakhulu, iyenza isithasiselo esibaluleke kakhulu phakathi kwabathandi bokufaneleka. Okungcono nakakhulu, akukho ukuqunjelwa noma ukugcinwa kwamanzi.
Umthamo onconyiwe ngu-3 kuya ku-5 mg nsuku zonke amasonto ayisishiyagalombili.
I-Nutrobal (Mk-677)
I-Ibutamoren noma i-Nutrobal (Mk-677) ingenye yama-SARM anethonya kakhulu futhi anokwethenjelwa ekulahlekelweni kwamafutha uma esetshenziswe ngendlela efanele. Ihlinzeka ngezindlela eziningi zokunciphisa amafutha, okwenza kube yisinqumo esihle kunoma ubani ofuna ukwehlisa amakhilogremu ambalwa anenkani.
Akugcini nje ngokukhuthaza ukukhiqizwa kwe-hormone yokukhula, kodwa futhi kubangela ukuthi umzimba wakho ukhulule ama-hormone adingekayo ekushiseni ama-fat reserves.
Kanye nokuhlinzeka ngosizo olukhulu ngokunciphisa amafutha, le SARM iyaziqhayisa ngokunakekelwa kwemisipha phakathi nemijikelezo yokuvinjelwa kwekhalori futhi ingasebenza njengesikhuthazi sokudla, ikusize uthole ibhalansi efanele yokudla okunomsoco ukuze uhlale usendleleni ngohambo lwakho lokufaneleka.
Ucwaningo kubantu lubonise ukuthi ukuphathwa komlomo kwansuku zonke kwe-MK-677 kubantu abadala abanempilo enempilo kuyakhuthazwa i-hormone yokukhula (GH) i-insulin-like growth factor axis kanye ne-IGF-binding protein ekhulayo. Ngenxa yalokho, kuthuthukisa imisipha yemisipha kanye namathambo.
Ama-SARM Angcono Kakhulu Wokunciphisa Isisindo
Ukulahlekelwa isisindo kungaba inqubo ende, kodwa ngokufanele Isitaki sama-SARM, kungase kube lula futhi kusheshe kunalokho ucabanga. Inhlanganisela yama-SARM ahlukene ingasiza ukukhomba amafutha anenkani, ukunciphisa ukudla nokwandisa amazinga wamandla ngenkathi ikubekela imiphumela emihle.
Cabangela ukungeza isitaki se-androgen receptor modulator (SARM) esikhethiwe esifanelana nemigomo yakho. Isitaki sakho kufanele sibe nama-SARM amabili noma ngaphezulu ukuze uthole okuningi kuwo. Izinketho ezidumile yi-LGD-4033, MK-677 kanye ne-Andarine yokugcinwa kwemisipha okuthuthukisiwe phakathi nemijikelezo yokusika kanye ne-Ostarine yemiphumela ethuthukisiwe yokushisa amafutha kulo lonke uhlelo lwakho lokudla.
Uma usukulungele ukufinyelela imigomo yakho yokulahlekelwa isisindo ngokushesha, kodwa kungokokuqala ukuthi ubeke ama-SARM, qala nge isitaki sokusika sabaqalayo.
Lapho Ukuthenga Ama-SARM Ukuze Unciphise Isisindo
Ukwehlisa isisindo kanye nokushiswa kwamafutha kuyimisebenzi eyinselele. Nokho, kungenzeka ukusheshisa inqubo ngosizo oluthile. Sibhale ama-SARM angcono kakhulu nezitaki zokulahlekelwa isisindo. Uma ubheka ukuthenga ama-SARM ukuze ulahlekelwe isisindo, qiniseka ukuthi uhlola Isitolo se-SARMS UK-Siqinisekisa ukuthi sihlinzeka ngemikhiqizo yekhwalithi ephezulu ngaso sonke isikhathi.