ISARMS UK
Uma uphakamisa njalo, mhlawumbe ubheka ukukha ngomzimba osikiwe wokugcina. Yonke impendulo futhi isethiwe iyitshe lokunyathela ekufinyeleleni ekubukeni kwe-vein-popping oyifunayo. Noma usebenza kanzima kanzima, ubonakala ngathi awusoze wafinyelela enhlosweni yakho. Uphakamisa njalo ngosuku olulodwa. Udla amaprotheni amaningi. Kodwa-ke awakhi imisipha eyanele ukubukeka inciphile futhi incike. Eqinisweni, ukude nalo.
Abantu abaningi basebenza kanzima kepha abakaze bafeze lokho kubukeka okuklebhukile. Kodwa-ke, kunendlela yokuthola uhlobo lomzimba olulangazelela kakhulu. Isinqamuleli uma uthanda. Kungenzeka ukuthi uzwile ngakho - ama-SARM.
Ama-modulators we-androgen receptor akhethiwe, noma ama-SARM, yisigaba esisha sezengezo esibizwa nge- "steroids esemthethweni." Ama-SAR yizidakamizwa ezikhuthaza ukusebenza kwakho kwezemidlalo nobukhulu bemisipha. Bafeza le nhloso ngokulingisa imiphumela ye-testosterone. Ngaphezu kwalokho ama-SAR awunayo imiphumela emibi i-steroids enayo, njengokuncipha kwamasende akho nokubanga ukuphazamiseka kwemizwelo.
Naphezu kokuphepha kwabo okuhlobene ne-steroids, kunempikiswano enkulu mayelana nama-SAR manje. Ungase uzwe ukuthi bangaba nemiphumela emibi ethile eyingozi. Mhlawumbe uzibuza ukuthi ungayithatha kanjani i-SARMS noma uma ifanele ingozi. Kulesi sihloko, sizobheka ngokujulile ama-SARM ahlukahlukene ukuze unqume ukuthi ngabe lezi zithasiselo zikulungele yini.
Mayelana nama-SARM
Ama-modulators we-androgen receptor akhethiwe (ama-SARM) iqoqo lama-compounds asebenza kuma-hormone akho ngendlela ebhekiswe kakhulu. Ama-SAR athuthukiswa ososayensi emashumini eminyaka adlule ukubhekana nezinguquko ezihlobene nobudala emandleni nasesiswini esiqala cishe eminyakeni yobudala ephakathi. Izifundo ezahlola ama-SARM ekuqaleni zazibheka usizo lwazo kubantu abalulama ekuhlinzweni kwe-hip, abesifazane abangemva kokuya esikhathini kanye neziguli ezinomdlavuza. Inhloso bekuwukusiza ukunciphisa ingozi yokuwa kwezicubu ezibuthakathaka kubantu abadala asebekhulile, ukunciphisa ukungasebenzi kahle komchamo okuphathelene nemisipha yamathambo ebuthakathaka nokuthuthukisa amandla eziguli ezinomdlavuza.
Okutholwe ngabaphenyi kulezi zivivinyo zomtholampilo ukuthi amaSARM ashisa amanoni futhi akhe imisipha ezingeni elifana ne-steroids. Ngokwengeziwe, ama-SAR enza lezi zinto ngaphandle kwemiphumela emibi ebonwa ngama-steroids. Abaphenyi baphetha ngokuthi kudingeka olunye ucwaningo kumaSARM ukunquma ukuphepha kokusebenzisa kwabo isikhathi eside. Kodwa-ke, abantu bathole izinzuzo zama-SARM futhi baqala ukwengeza nabo. Izinkulungwane zamadoda ezivela kuzo zonke izizinda zisebenzisa ama-SARM ukwakha ubukhulu bemisipha nokunciphisa amafutha.
Izinzuzo zamaSARM
Nazi ezinye izinzuzo zama-SARM.
- Yakha umsipha omncane. Ama-SAR alungele noma ngubani ofuna ukwakha imisipha ngokushesha.
- Chitha amafutha. Ama-SARM atholakele ukusiza ukwehlisa isisindo samafutha. Lezi zinhlanganisela zingasiza ukuchitha amafutha.
- Khulisa ukuminyana kwethambo. Olunye ucwaningo olushicilelwe ngabaphenyi e-Ohio State University luthole ukuthi amaSARM akhulise kakhulu amandla amathambo ngenkathi anciphisa amafutha. Abaphenyi bahlongoza ukwelashwa kwamaSARM njengendlela yokwehlisa ukulahleka kwemisipha kubantu abanesifo.
Izinhlobo zama-SARM
Kunezinhlobo ezahlukahlukene zama-SARM atholakalayo emakethe. I-SARM ngqo yakho incike ezinhlosweni zakho. Amanye ama-SARM angcono esigabeni sokusika kanti amanye asezinsizeni. Nazi izinhlobo ezinkulu zama-SARM.
I-Ligandrol (LGD-4033)
ILigandrol noma I-LGD-4033 yasungulwa yiLigand Pharmaceuticals yokwelapha ukuchitheka kwemisipha ezigulini ezinomdlavuza nezinye izifo. Okwamanje kusezivivinyweni zokwelashwa ukuthola ukuvunywa kwe-FDA. Le nhlanganisela yaziwa njengenye yama-SARM anamandla kakhulu emakethe. Kuholela ekuzuzeni okukhulu emisipha namandla. Imiphumela ye-LGD-4033 ihlala isikhathi eside, ikakhulukazi uma ihlanganiswe nama-macros afanele.
I-Ostraine (MK-2866)
Ostraine noma I-MK-2866 ingenye yama-SARM amasha atholakalayo. Le nhlanganisela nayo yadalelwa ukuphatha ukuchitheka kwemisipha. Ibuye isetshenziselwe ukwelashwa okufaka esikhundleni se-testosterone. I-MK-2866 ikhiqiza ukuzuza okuhlala isikhathi eside futhi okuphawulekayo emandleni nasekuzuzeni kwemisipha emincane. Le SARM nayo itholakale ukuthi inyusa ukuqina kwamathambo. I-Ligandrol (i-LGD-4033) ne-Ostraine (MK-2866) yi-SARMS efanayo. Funda kabanzi ngalaba ababili kulokhu okuthunyelwe kwebhulogi kuqhathanisa i-LGD-4033 vs. MK-2866.
I-Cardarine (i-GW-501516)
I-Cardarine (GW-501516) yi-SARM engeyona eye-hormonal. Le nhlanganisela, ebizwa nangokuthi i-Endurabol, yasungulwa ekuqaleni ngama-1990s nguLigand noGlaxoSmithKline ukunciphisa izicubu. Yashiywa yilezi zinkampani ezenza imithi njengoba yayingasebenzeli leyo nhloso. Kepha, kwatholakala ngesikhathi sokuhlolwa komtholampilo ukuthi le nhlanganisela yayimangalisa ngenye indlela. Ilahla amafutha futhi ithuthukise ukukhuthazela kakhulu. Namuhla ingenye yezindlela ezithandwa kakhulu zokulahleka kwamafutha nokukhuthazela.
I-Andarine (S4)
Njengamanye ama-SARM, Andarine ekuqaleni yayihloselwe ukwelapha ukonakala kwemisipha. Ososayensi bathola ukuthi ingenye yama-SARM okusika amafutha anamandla kakhulu laphaya. I-S4 ilungele ukusika amafutha esisu anenkani. Ngalesi sizathu, idume kakhulu ngokusika imijikelezo. I-Andarine nayo ilungele ukukhwabanisa, futhi.
I-Stenabolic (SR-9009)
Le nhlanganisela yenzelwe abasubathi. Kuyasiza ukukhulisa ukubekezela futhi kuhle ekulahlekelweni kwamafutha. I-SR-9009 inyusa ukushiswa kwekhalori ngamaphesenti ama-5. I-Stenabolic iphinda izinzuzo zokuzivocavoca noma ngabe umzimba uphumule. Kukhuthaza amandla, ukusebenza, nokukhuthazela.
Imiphumela emibi ye-SARM
Njengazo zonke izengezo nemithi, ama-SAR anemiphumela engemihle. Ngokuya nge-WebMD, cishe yonke imithi - kusuka ku-aspirin eyisisekelo kuya kuma-SARM - inamandla okudala imiphumela emibi. Isikhathi esiningi, imiphumela emibi yenzeke kubasebenzisi abambalwa kuphela. Iningi lemiphumela engemihle lincane. Ingozi yemiphumela emibi ye-SARM iyanda uma uthatha okungaphezu komthamo wansuku zonke onconyiwe. Ngabe uyazibuza ukuthi ungathatha kanjani ama-SARMS ukugwema imiphumela emibi? Indlela ephephe kunazo zonke ukunamathela kumthamo ophakanyisiwe.
Ekuphetheni, ama-SARMS afakazelwe ngokwesayensi ukuthi akhe imisipha futhi ashise amanoni. Banikeza izinzuzo eziningi ezifanayo zokwakha umzimba we-steroids kodwa ngaphandle kwemiphumela emibi kakhulu. Bhalisela amadili akhethekile nokukhushulwa. Ukuhambisana nezindaba zakamuva kwa-SARS, silandele.
References:
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2602589/
- https://www.nytimes.com/2018/04/12/well/move/sarms-muscle-body-building-weight-lifting-pill-supplements-safety.html
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2039878/
- https://www.webmd.com/a-to-z-guides/drug-side-effects-explained#1