Yimaphi ama-SARM okufanele ngiwathathe ngo-2020?
Uma ubukade ubheke izinhlobo ezahlukahlukene ze-Selective androgen receptor modulators (SARMs) kepha udidekile ukuthi iyiphi oyithengayo futhi uyisebenzise, lolu lwazi Amaphrofayili weSARMkungaba wusizo kuwe ngaphezu kwendlela nje.
I-Ostarine (MK-2866)
Ostarine, eyaziwa nangokuthi I-MK-2866 noma i-Ostabolic, iyimoduli ekhethiwe ye-androgen receptor modulator (SARM) ethathwa njengenye ye izidakamizwa zokusika ezihamba phambili. Le SARM inamandla okuba nomthelela omuhle futhi obalulekile kwimpilo yamathambo nobukhulu bemisipha. Ngokomtholampilo, i-Ostarine ikhonjiswa ezigulini ezitholwa zinezinkinga zempilo ezifana nokuhlobene nobudala ukuchitheka kwemisipha.
I-Ostarine, njengabo bonke Ama-SAR, inamandla okubopha nokwenza kusebenze ama-androgen receptors ekwakheni umfutho emazingeni we-protein synthesis. Ngaphezu kwalokho, i-MK-2866 inenzuzo yokuvikela noma yiluphi uhlobo lwemiphumela ehlekisayo futhi yenza amandla nemisipha izuze kalula. Into enhle kakhulu ukuthi lezi zinzuzo eziyingqayizivele ze-Ostarine zingatholwa ngabasubathi bamandla, abakhi bomzimba, nabanye ngaphandle kokusondela emiphumeleni emibi njengokukhuliswa kwe-prostate nokuvalwa kwe nezindlala pituitary.
I-MK-2866 yaziwa nangokuthi ithuthukisa impilo ehlangene futhi inyuse ubukhulu bethambo. Lokhu ikwenza ngokuthuthukisa amazinga wokuqina kwamathambo emzimbeni ngenxa yemiphumela ye-anabolic emisipheni yamathambo nezicubu ezixhuma. Uma lokho kungagcini lapho, i-Ostarine ayikhuthazi ukwanda kwamazinga e-estrogen njengoba kungekho ukunambitheka okuhambisana nakho okusetshenziswa kwalenhlanganisela. Ngaphezu kwalokho, akubangeli i-dihydrotestosterone (DHT) izingqinamba ezifana nokulahleka kwezinwele. Futhi akuholeli ekwenziweni kwe-nortestosterone okungenzeka kube nomthelela omubi empilweni yezocansi kanye ne-libido.
Ama-bodybuilders nabantu abathanda ukuqina basebenzisa i-Ostabolic ku-on noma off-cycle ukukhulisa noma ukugcina isisindo somzimba esinciphile ngenkathi kushiswa amafutha. Kungenxa yalesi sizathu ukuthi i-Ostabolic ithandwa kakhulu phakathi kwababhukudi, abagijimi bamandla, abagibeli bamabhayisikili, kanye nabasindisi besisindo abafuna isidakamizwa esinamandla esithuthukisa ukusebenza esingabasiza ngamandla, ukukhuthazela, nobukhulu bemisipha. I-Ostabolic iyasiza futhi ukuvimbela nokupholisa ukulimala okungapheli esikhathini esifushane. Lokhu kusiza abasebenzisi ukuthi bahlale kwifomu eliphezulu unyaka nonyaka okubasizayo ukuthi bacindezele isikhathi eside nangaphezulu kuyo yonke iminyaka yabo yokuncintisana nokungancintisani.
I-Ostabolic ibekwe kahle emithamo yansuku zonke ye-50mg nsuku zonke namanye ama-SAR afana ne-Cardarine 20mg nsuku zonke, i-Andarine 25mg nsuku zonke, nama-7 caps we-N2Guard nsuku zonke kumjikelezo wamaviki e-8. Lokhu kungalandelwa yi-25mg ye-Ostabolic nsuku zonke, i-Stenabolic 10mg nsuku zonke, i-Cardarine 10mg nsuku zonke, ama-caps we-7 we-N2Guard nsuku zonke, ne-10mg ye I-LGD-4033nsuku zonke amasonto ayisishiyagalombili alandelayo. Kunconywa ukwelashwa kokujikeleza kwamaviki ama-8 futhi kufanele kufake iClomid 4mg nsuku zonke, iCardarine 25mg nsuku zonke, amaphilisi e-HCGenerate ES 10 ngosuku, kanye neSARMS Mini PCT.
I-Stenabolic (SR-9009)
Ihlukaniswe njenge-agonist ye- UMfu-ErbA, I-Stenabolic (SR-9009) yasungulwa ekuqaleni ukunciphisa umonakalo we-mitochondrial nokwandisa ukukhuthazela. Le nhlanganisela ithandwa kakhulu ngabasubathi emkhakheni weCrossFit kanye ukukhuthazela ezemidlalo. I-Stenabolic (SR-9009) empeleni isebenza kakhulu njenge-GW-501516 kepha isebenza kangcono kuneCardarine ngezindlela eziningi.
Enye enkulu kakhulu izinzuzo ze-Stenabolic(SR-9009) ukuthi ithuthukisa kakhulu amandla okuvivinya umzimba nokuzivocavoca nge-mitochondria emisipheni yamathambo. Kusebenza ngokulinganayo ekushiseni amafutha ne-glucose emisipheni nokulinganisa amazinga e-cholesterol emzimbeni. Ngaphezu kwalokho, iStenabolic (SR-9009) inaleli khono elimangalisayo lokuthuthukisa imetabolism noma ngabe umzimba ukwimodi yokuphumula. Ngamafuphi, abasebenzisi be-Stenabolic bangalindela ukuncipha kwamafutha omzimba, ukubukeka komzimba okuthuthukisiwe, ukusebenza kahle, kanye nokuthuthuka komqondo ngokusebenzisa inhlanganisela isikhathi esifushane samaviki angu-6-8.
I-stenabolic ingasetshenziswa wedwa, ngesikhathi sebhuloho, noma ngesikhathi sokwelapha umjikelezo weposi. Kungalindelwa ukuthi ikusize ucindezele kanzima futhi isikhathi eside ngesikhathi sokuzivocavoca okukhulu futhi ugcine amanoni anesisu esiswini nawama-visceral ngaphandle kwesithombe. Lokhu kuzokusiza ukuthi ubambe isisindo semisipha nesimo esifinyelelwe kalula ngesikhathi nangemva kwe- Umjikelezo wamaSARM. I-Stenabolic isetshenziswa kahle emithamo yansuku zonke ye-10-20mg ngabasebenzisi besilisa kanye nemithamo yansuku zonke engu-5-10mg ngabasebenzisi besifazane.
I-Andarine (i-S-4)
Okudume kakhulu njenge-S-4, Andarineyisidakamizwa esinamandla esithuthukisa ukusebenza esithandwa ngokwedlulele ngabakhi bomzimba abangochwepheshe. Ngokomtholampilo, le SARM ikhonjiswa kubantu abatholakala ukuthi banezimo zezempilo njengokuchitheka kwemisipha, i-benign prostatic hypertrophy, ne-osteoporosis. I-Andarine, uma iqhathaniswa namanye ama-SARM, ingokwemvelo elondolozekayo ngokuqondene nemiphumela ye-anabolic ne-androgenic.
Ukusebenza njenge-agonist eyingxenye yomlomo esebenzayo ye-androgen receptors, u-Andarine unamandla okunciphisa isisindo sendlala I-Finasteridekepha ngaphandle kokuncipha kwemisipha noma imiphumela emibi ye-anti-androgenic. Lokhu kusho ukuthi abasebenzisi be-S-4 akudingeki bakhathazeke ngokubuyela emuva kwezinwele noma ukulahleka kwezinwele okungenye yezinto ezisatshwa kakhulu imiphumela emibi ye-anabolic steroids. Kuyaziwa phakathi kwabesilisa nabesifazane. I-S-4 inekhono lokunamathisela cishe uhhafu ngempumelelo njenge-testosterone eqondile kepha ngaphandle kokuholela emiphumeleni emibi ye-androgenic ejwayelekile nge-testosterone.
Enye enkulu kakhulu izinzuzo ze-Andarineukuthi kuthuthukisa ukukhuthazela, kunciphisa amanoni, futhi kusiza ngempilo ehlangene neyethambo. Abasebenzisi be-Andarine bangalindela ukuthi bazuze ekuzuzeni kwemisipha emile nokuqinisa amandla ngaphandle kokukhathazeka ngokuthwala amanzi amaningi ngoba akubangeli ukuvuvukala. Lezi zinzuzo zenza u-Andarine inketho enhle kuwo wonke umuntu, ikakhulukazi ama-powerlifters afuna onamandla Umjikelezo weSARMukwenza isigaba sabo sesisindo. Hhayi lokhu kuphela, u-Andarine usebenza kahle ngamakhemikhali avela ku-DHT futhi engeza okumangazayo kufayela le- ukusika isitaki. I-Andarine ifakwe kahle kakhulu nge-LGD-4033 ne-GW-501516. Ingabekwa futhi nge-MK-2866 futhi I-MK-677. Ngenye indlela, ingahlanganiswa nesitaki se-anabolic steroid njengoba izonikeza izinzuzo ezinkulu kumjikelezo ngaphandle kokungeza kuwo imiphumela emibi ye-steroid.
I-Nutrobal (MK-677)
Eyaziwa nangokuthi i-Ibutamoren neMK-677, iNutrobal iyi-agonist ekhethiwe yama-ghrelin receptors. Ngokomtholampilo, iNutrabol inqunyelwe ukuphatha amazinga ancishisiwe e-IGF-1 (insulini efana nokukhula kwe-insulin 1) ne-hormone yokukhula, ikakhulukazi ezinganeni nasebekhulile.
I-Nutrobal iyindlela enhle ehlukile kwi-Human growth hormone ngezindlela eziningi. I-HGH ibiza ngokweqile ukukhiqiza nokuthenga futhi yingakho iningi labantu lithenga i-HGH ejwayelekile evela emazweni afana neChina. Esikhathini esedlule, kube nezikhalazo eziningi ngobumsulwa, ukusebenza kahle, ukuphepha, namazinga ekhwalithi yale HGH. Akukona nje kuphela lokhu, abakhiqizi abaningi be-GH yamaShayina basolwa ngisho nangokungeza izinto eziyingozi njenge-arsenic ne-mercury ku-hormone yokukhula ejwayelekile.
INutrobal isebenza ngokulingisa indlela yokusebenza kwe-ghrelin, i-peptide hormone engapheli, elawula ukudla. Iphinde ibambe iqhaza elibaluleke kakhulu ekulawulweni kokusatshalaliswa kwamandla. Ngaphezu kwalokhu, i-MK-677 inyusa amazinga e-IGF-1 ne-GH emzimbeni ngaphandle kokukhuthaza ukwanda kwesibalo samahomoni aqeda imisipha njenge-cortisol.
Into enhle kakhulu ukuthi iNutrabol, ngokungafani ne-hormone yokukhula exogenous, ayicindezeli ikhono lomzimba ukukhiqiza ngokwemvelo i-hormone yokukhula. Uma kungagcini lapho, iNutrabol ingavimbela ngisho nohlobo 2 lwesifo sikashukela nokukhuluphala ngokweqile. Kusebenza ngokulinganayo ukuthuthukisa ukukhuthazela, ukuqina, inhlalakahle, ithambo nempilo ehlangene, impilo yonke nokulala. Ngale ndlela, iNutrabol empeleni ithuthukisa amakhono jikelele wabasubathi nabanye njengoba benamandla amaningi usuku lonke.
I-Nutrabol isetshenziswa kangcono emithamo yansuku zonke ye-10-50mg nsuku zonke, okungcono ngokudla. Ingangezwa kusitaki se-SARM noma kumjikelezo we-anabolic steroid. Umjikelezo ofanele weNutrabol ungaba neNutrabol, GW-501516, Andarine, neN2guard kulandele ukwelashwa komjikelezo weposi.
I-Cardarine (i-GW-501516)
I-Peroxisome proliferator-activated receptor beta / delta agonist, GW-501516 (eyaziwa nangokuthi i-Endurobol, Cardarine, ne-GSK-516) ingenye yama-SARM adume kakhulu. ICardarine yaziwa kakhulu ngamakhono ayo amangalisayo okwehlisa ushukela egazini futhi ama-triglycerides.
Iphinde ithuthukise izinga lempilo yenhliziyo kanye nele cholesterol. Akukona nje kuphela lokhu, uCarardarine ufakazela ukuthi ungeza kakhulu ekusikeni kanye nasekujikeleziseni imijikelezo ngokukhuthaza ukukhuthazela, ukuqina, isisindo somzimba esinciphile, imithambo, inhlalakahle, amaprotheni synthesis, kanye ukugcinwa kwe-nitrogen. I-Cardarine isetshenziswa kangcono emithonjeni yansuku zonke ye-10-20mg, okungcono ngokudla komjikelezo wamaviki e-8-12. Ibekwe kahle kakhulu nge-RAD-140, MK-2866, ne-LGD-4033.
I-Anabolicum (LGD-4033)
Eyaziwa nangokuthi i-LGD noma i-Anabolicum, i-LGD-4033 yasungulwa ekuqaleni ukwelapha izimo zezempilo ezinjenge-osteoporosis kanye nokuchitheka kwemisipha. Kamuva, yathola ukuthandwa njengesengezo sokwakha imisipha nokwakha umzimba. Ilungele bobabili abesilisa nabesifazane, i-LGD-4033 ivuselela ukuthuthuka okukhulu emazingeni we-muscle mass, amandla, ukukhuthazela, nokusebenza kokuzivocavoca ngaphandle kokubanga imiphumela emibi efana ne-steroid.
Sithemba ukuthi lo mhlahlandlela ku Amaphrofayili weSARMibilusizo kuwe ngaphezu nje kwendlela.