Ama-SAR kungathathwa njengezithasiselo ezintsha impela emhlabeni wokwakha umzimba, kepha empeleni, zifundelwe ukusetshenziswa okungahle kwenzeke ezimweni ezinjengemisipha yokuchitha isifo isikhashana.
Abasubathi abaningi baluthathile lolu cwaningo balusebenzisa ukwenza ngcono ukusebenza noma ukuthuthukisa umzimba wabo ukwenza ngcono ukusebenza endaweni yokuncintisana. Ama-SAR ukwesekwa kungathola indawo esakhiweni semisipha noma kuhlelo lokushisa amafutha, futhi imiphumela ingaba isimanga nakakhulu uma ihlanganiswe kahle.
Ukuthola kabusha kusuka ku-anabolic steroid noma iprohormone umjikelezo, sekuthandwayo ukusetshenziswa Ama-SAR. Kuyasiza ukwazi ukuthi kwenzekani emzimbeni womuntu ngemuva kokuqedwa komjikelezo we-steroid ukuqonda isizathu salokhu.
Ukunqamula umjikelezo wama-SARM
Ukuthatha izithako zokusekelwa komjikelezo, noma ngabe ama-steroids noma ama-prohormones, anciphisa ukukhiqizwa kwamahomoni emvelo komzimba. Umzimba uthola ubuningi be-androgens bese uthumela isinali ku-hypothalamus ukunciphisa ukukhishwa kwe-gonadorelin. Lokhu kwehliswa kuholela ekwehlisweni kokukhiqizwa kwamahomoni e-luteinizing nama-hormone ashukumisayo e-follicle ngendlala ye-pituitary. Lokhu kwehla, kumisa ukukhiqizwa kwe-testosterone kumaseli eLeydig emasendeni; lokhu kubizwa ngempendulo engeyinhle. Yisizathu sokuthi izivivinyo ze-atrophy noma zehle ngosayizi ngesikhathi se- Umjikelezo weSARM.
Umgomo wokwelashwa okubuyisela esimeni ukwenza isimo esisheshayo sikhiqize umzimba ama-hormone futhi ukhombise umzimba ukuthi uqalise kabusha ukukhiqizwa kwe-testosterone.
Amakhemikhali ajwayelekile futhi asebenza kahle asetshenziselwa le njongo yi-tamoxifen citrate ne-clomiphene citrate.
I-Tamoxifen ne-Clomid zisetshenziswa ngokushesha ngemuva kwe- umjikelezo wamaSARM ukubuyisela umzimba emazingeni e-hormone ejwayelekile ngokushesha okukhulu. Kodwa-ke, noma ngabe kusetshenziswa iTamoxifen neClomid, kusekhona ukubambezeleka okuncane ekubuyisweni kwamazinga ajwayelekile e-hormonal. Kungalesi sikhathi lapho kubonakala ukulahleka okuphawuleka kakhulu kwemisipha namandla.
Ukusetshenziswa kwe-Ostarine ekwelashweni okushintshayo
Ostarine ibopha ngokukhetha kuma-androgen receptors emisipheni nasemathanjeni; iyaqhubeka nokwenza kusebenze i-androgen receptor, kuyilapho i-Tamoxifen ne-Clomid bejwayelekile ukukhiqizwa kwe-testosterone yemvelo.
Ngenxa yalokhu kusebenze okuqhubekayo emisipheni, kunciphisa ukulahleka kwemisipha namandla ngesikhathi sokululama. Abasebenzisi abaningi babika nokwanda kwamandla ngaphezu kwemiphumela etholwe phakathi nomjikelezo we-steroid.
- Ukusetshenziswa kokudla. Ama-calories angesinye isici esibalulekile ngesikhathi sokululama. Uhlelo lwe-endocrine, ngemuva komjikelezo, alikwazi ukusebenza kahle. Umzimba ulwela i-homeostasis, nangemva kwe- umjikelezo wamaSARM, kuvame ukuba sesimweni sokukhuphuka, okungajwayelekile ngayo, inani lesisindo. Ukudla ikhalori kufanele kube okufanayo noma ngisho nangaphezulu kunangesikhathi somjikelezo wokugcina lolu bunzima (ikakhulukazi uma ingekho indawo efanelekile yamahomoni).
Ngisho nokwazi lokhu, abanye abasebenzisi bayanqikaza ukusebenzisa la makhalori lapho bemisa umjikelezo we-steroid ngenxa yengozi yokwanda kwamafutha omzimba.
Umphumela we-anabolic ne-metabolic we Ostarine kuzovumela umsebenzisi ukuthi agcine ukudla kwe-caloric ngesikhathi sokwelashwa kokuvuselela ngaphandle kokukhulisa inani lamafutha.
Kunzima ukukugcina lokhu nokugcina isisindo esitholwe ngokuphelele (kuhlala kukhona ukulahleka kwamanzi kanye ne-glycogen ngemuva kwe- Umjikelezo weSARM); amakhalori akhuphukile azonikeza umzimba isikhathi esengeziwe sokujwayela ivolumu entsha yemisipha.
Amandla ayagcinwa noma aze andiswe; okungukuthi, akukho ukulahleka kwemisipha, futhi ngisho nokwanda okuncane kuyo kuyabonakala.
Ostarine yakhelwe ukunciphisa ukucindezelwa kwamazinga e-testosterone akhiqizwa ngumzimba. Ngakho-ke, i-Tamoxifen ne-Clomid izosiza ukubuyisa amazinga emvelo e-testosterone abuyele kokujwayelekile, kanti i-Ostarine izokwenza kusebenze ama-androgen receptors.
Ungayisebenzisa kanjani i-Ostarine yezinsiza zokusekelwa komjikelezo?
Umthetho olandelwayo ovamile kakhulu umthamo ophelele ekuqaleni kokusetshenziswa bese ususa umthamo esikhathini esisele sesikhathi sokululama. I-protocol yokulinganisa ejwayelekile ifaka ama-25 mg amasonto ama-4-5. Njengoba isigamu sempilo ye-Ostarine cishe singamahora angama-24, umuthi udinga ukuphuzwa kanye kuphela ngosuku.
Kusukela imiphumela ye Tamoxifen futhi I-Clomid azibonakali ngokushesha, i-Ostarine izohlinzeka ngokusebenza okukhulu kwama-androgen receptors kuzicubu zemisipha uma kungekho ama-hormone endogenous. Noma uthatha i-Tamoxifen ne-Clomid, i-25 mg ye-Ostarine ngesikhathi sokululama izokunikeza izinzuzo ze-androgen receptor agonism, cishe kungacindezelwa i-testosterone. Abasebenzisi abaningi bakhuluma ngezinzuzo zokwanda kokuthatha umuthi amasonto ama-5-8.
Ngakho-ke, ukusebenzisa i- Ostarine, ngaphandle kwemiphumela ye-androgenic, kuyisinqumo esihle kakhulu sokugcina nokwandisa ubukhulu bemisipha nokusebenza ngemuva kwe- Umjikelezo weSARM.
Kungani uhlanganisa ama-SARM?
Kunezizathu eziningana zokuthi kungani ungafuna ukufaka ama-SARM. Uma usaqala, kungcono uqale ngento eyodwa I-SARM ukuhlola ukuthi umzimba wakho uphendula kanjani kuwo futhi unqume ukuthi yiziphi izici zomkhiqizo owuthandayo (noma ongazithandi).
The Umjikelezo weSARM kuyindlela enengqondo yokuthuthukisa ukusebenza kokuzivocavoca kwakho. Ungavuna izinzuzo ezimbili ezihlukene Ama-SAR. Isibonelo, ukugqama kokunye kungaba wukudla okunempilo kokushiswa kwamafutha, kuyilapho okugqamisiwe kokunye kungabuyiselwa ngokushesha.
Isitaki sisho nokuthi ungasebenzisa umthamo ophansi we umjikelezo wamaSARM, ukunciphisa ubungozi okuqhamuka uma udla imishanguzo ukwedlula umthamo omkhulu wenhlanganisela eyodwa; lokhu kuyiqiniso ikakhulukazi uma usebenzisa okuthile okungafani nehomoni I-Cardarin noma iMK-677.
Yimuphi Umjikelezo weSARM Okungcono Ukuthatha?
- I-Ostarine (MK-2866) (i-SARM engcono kakhulu jikelele). I-Ostarine inocwaningo lwabantu kunawo wonke ama-SARM. Kuyindlela eguquguqukayo emangalisayo yokushiswa kwamafutha nokukhwabanisa, kanye ne- okuqhamuka uma udla imishanguzo mancane kakhulu emazingeni aphansi ukuya kwelinganiselayo uma esetshenziswa ngokuhlakanipha. Uma ungakaze usebenzise i I-SARM ngaphambili, lokhu kuzoba ukukhetha kwakho kokuqala.
- I-Andarin (S-4) (ukukhetha okungcono kwabesifazane). U-Andarin mncane impela I-SARM futhi ingenye yezindlela ezingcono kakhulu zabesifazane. Eyaziwa nangokuthi i-S4, ingasiza ukukhulisa ubukhulu bemisipha nokubuyiselwa komzimba.
- Ligandrol (LGD-4033) (ilungele ukuzuza isisindo). Ligandrol kukholakala ukuthi inamandla aphindwe kayishumi kune Ostarine, kukusiza ukuthi uthole isisindo semisipha nevolumu ngesikhathi esincane. Isinyathelo esihle kulabo abashayayo.
- I-Radarin (RAD-140). I-Radarine, noma i-Testolone, ingenye yama-SARM athandwa kakhulu. Iyathandwa ngezinzuzo zayo zokusebenza, ukuvuselelwa, nokuzuza kwemisipha. I-Radarine ingasetshenziselwa ukuma yodwa okokuqala kwakho umjikelezo noma isongwe nezinye Ama-SAR.
- I-YK-11 (i-SARM enamandla kakhulu). Uma ubusebenzisa Ama-SAR isikhathi esithile futhi ngazama izinketho ezingenhla nokufakwa isitaki, khona-ke i-YK-11 ivala igebe phakathi Ama-SAR nama-prohormones. I-SARM enamandla ihlala isebenzisa ukusekelwa okugcwele komjikelezo futhi igcina isikhathi sokusetshenziswa sibe sifushane ngangokunokwenzeka.
- I-Ibutamoren (MK-677). I-Ibutamoren inomphumela onamandla wokuqinisa isifiso sokudla futhi ingasiza ukulala iphinde ilulame ekukhuleni kwe-hormone ekhulayo. Ilungele ukustaka ukuthola isisindo.
- I-Cardarin (GW501516). I-Cardarin isebenza ngendlela ye-PPAR yokwandisa ukukhuthazela, ukukhuthaza iphrofayili ye-lipid enempilo, nokusekela ukulahleka kwamafutha.
Ukwelashwa kokujikeleza ngemuva kokujikeleza kwama-SARM
Ukwelashwa kokujikeleza ngemuva kokusebenzisa ama-SARM kuzohluka ngokuya nge Ama-SAR isetshenzisiwe, umthamo, nobude bomjikelezo. Kodwa-ke, ngokujwayelekile, ungaqedela ukwelashwa ngemuva komjikelezo usebenzisa izengezo ezingaphezulu kwamakhompiyutha ngenxa yemvelo ekhethiwe yama-SARM, okusho ukuthi okuqhamuka uma udla imishanguzo mancane amathuba futhi kungenzeka angabi namandla lapho enza imizimba yenyama.
Kufanele ube ne-testosterone booster enamandla ukuze usize umzimba wakho uqalise ukukhiqizwa kwe-testosterone engapheli futhi ubuyise amazinga we-testosterone yemvelo enempilo. Ukucindezela i-testosterone kungaba yingozi nganoma yisiphi isengezo se-hormone, ngakho-ke ngaphandle kokuhlolwa kwegazi ukuqinisekisa isimo se-hormonal ngemuva komjikelezo, into engcono kakhulu ongayenza ukunaka umzimba wakho futhi uwusize lapho ungakwazi khona.
Uma usebenzisa imithamo ephakeme noma enamandla Ama-SAR, uzodinga ukuba nezithako zokulawula i-estrogen. Lezi zithasiselo zicindezela i-enzyme ye-aromatase, ngakho-ke i-testosterone ayinakuguqulwa ibe yi-estrogen. Isenzo sayo sizosiza futhi ukwehlisa amazinga e-cortisol futhi kwandise amazinga e-testosterone ngokuhlukile kune-booster testosterone.
Ungahle uthande ukusebenzisa i-Natural Muscle Stimulant Ama-SAR ukukusiza ungene esimweni esihle sokugcina izinzuzo zakho zomjikelezo futhi uqhubeke uthuthuka.