Ingabe ama-SARM aphephile?

Ama-SARM (ama-Selective Androgen Receptor Modulators) asedume kakhulu e-UK, e-US, nakwezinye izingxenye zomhlaba ngokwakha imisipha kanye nemiphumela yokwehlisa isisindo. Abafani ne-steroids yendabuko, ngoba abakhiqizi imiphumela eyingozi efanayo, futhi abasubathi abaningi, abaqeqeshi, nabaqeqeshi bokuqina bayayisebenzisa ukugcina umzimba wabo oyifunayo.

Ukuphela kwendlela ozobona ngayo imiphumela emihle yokusebenzisa amaSARM ukukhetha umkhiqizo onedumela nokuthatha isilinganiso esinconyiwe. Kunezinhlobo ezahlukahlukene zama-SARM, futhi ngalinye linobude bomjikelezo ohlukile. Uma uthenga ama-SARM, funda ilebuli ngokucophelela bese uthatha inani elidingekayo ngezikhathi ezifanele. Amanye ama-SARM afana ne-Ibutamoren athathwa kahle phakathi nobusuku, kanti amanye athathwa kanye noma kabili ngosuku kuya ngokuhlushwa kwawo.

 

Izinzuzo zama-SARM: Ingabe ama-SARM aphephile?

• Ama-SAR angakuzuzisa ngezindlela eziningi. Basiza ekwelapheni ukulimala okudala, bathuthukisa ukuqina kwamathambo, futhi basiza abantu abanezinkinga zesibeletho. Ngokungafani nezinye izindlela zokwelapha azilimazi isibindi ngenkathi zenza kanjalo. 
• Abaphenyi basebenza futhi ukusebenzisa ama-SARM njengokwelapha kwe-Alzheimer's and osteoporosis ngokuzayo. 
• AmaSARM awanabo ubuthi, futhi ahlinzeka ngezinzuzo zezithako ze-anabolic ngenkathi kuncishiswa imiphumela emibi ye-testosterone.

 

Ama-SAR anomphumela onamandla kakhulu we-anabolic, futhi anamathisela kuma-receptors ngokukhetha ukukhulisa ubukhulu bemisipha namandla omzimba. Imiphumela emibi kuma-SARM ancishiswe kakhulu uma kuqhathaniswa ne-anabolic steroids ngenxa yalesi sizathu, ngoba isebenza kuphela kuma-receptors enza isenzo se-anabolic. Lezi zinto zamakhemikhali zisiza ekushiseni amafutha ngokushesha, yingakho zisetshenziswa kakhulu njengezithasiselo ngabantu abafuna ukuba sesimweni. Izengezo ze-SARM zingangena kalula ngomlomo ngaphandle kwesidingo semijovo.

Kunezinhlobo eziningi zama-SARM atholakalayo asetshenziselwa izinhloso ezahlukahlukene. Izengezo ezijwayelekile zeSARM ezaziwa ngokuzuza kwemisipha nokukhulisa isisindo somzimba esinciphile I-RAD-140, I-LGD-4033 futhi Andarine (owaziwa nangokuthi yi-S4).

Uhlobo oluvame kakhulu lwe-SARM olusetshenziselwa ukwakha amandla yi-MK2866, noma i-Ostarine. I-RAD-140 iyi-anabolic kakhulu futhi ingasetshenziselwa ukukhulisa amandla. Noma kunjalo, inamandla kakhulu kune-Ostarine, ngakho-ke idinga ukuthathwa ngamanani amancane.

Ekwakhiweni kwemisipha emile, ama-SARM afana ne-SR-9009, GW-1516, neMK-677 (Ibutamoren) asetshenziswa kakhulu. I-MK-677 empeleni iyasiza ekuthuthukiseni ukulala, futhi abantu abakuthola kunzima ukulala, ukulala, noma ukuthola ubuthongo bekhwalithi obukhulu bangazuza kulokhu kuxhaswa. 

Ama-SARM anciphisa ukubola kwamaprotheni asiza ekwakheni izicubu zemisipha. Izinsiza zabo zesenzo se-anabolic ekwakheni isisindo somzimba esinciphile, okusho ukuthi isisindo osibekayo sizobe singenamafutha namanzi. Lokhu kuqinisekisa ukwakheka komzimba okuhle ngaphandle kokufaka isisindo samanzi esizolahleka futhi ngokushesha.

Ama-SAR angasiza futhi ekuqiniseni imisipha, ngakho-ke abakhi bomzimba bangaphakamisa izinsimbi ezisindayo kalula futhi ngobuningi ngokuhamba kwesikhathi. Ukufakwa ngomlomo kwama-supplements kusho ukuthi kuphephe ukusetshenziswa uma kuqhathaniswa nemijovo engadala ukutheleleka kwesikhumba, noma nezinkinga zokungcola uma kungenakwenziwa ngendlela efanele.

 

Imiphumela emibi engaba khona

Uzobona kuphela imiphumela emibi noma imiphumela emibi uma ungathathi isengezo esilinganisweni esinconyiwe, noma uma ungawuqedi wonke umjikelezo wama-SARM. Ngokuhambisana nalokhu, futhi udinga ukugcina ukudla okunempilo futhi usebenze njalo, ukuze ukwazi ukubona izinzuzo esikhathini esifushane.

Lokhu kungukuhlangenwe nakho okusha komzimba wakho futhi ubunzima obukhuphukile balokhu bungayibeka ngaphansi kwengcindezi, kukwenze uthambekele kakhulu emiphumeleni emibi futhi unciphise inqubekela phambili yakho ngokuhamba kwesikhathi. Ngaphakathi nangaphandle kohambo lwakho lokuqina, impilo kufanele ibekwe phambili futhi ukudla okunempilo, ukulala ngokwanele, nokucwaninga okufanelekile kuyisisekelo esihle sanoma imuphi umbuso wezemidlalo. Uma wenza umzamo owengeziwe kulezi zakhiwo, uthola imiphumela engcono kakhulu.

Njengoba kushiwo ngaphambili, kubalulekile ukuzungeza futhi uqiniseke ukuthi uthenga kuphela izithasiselo emithonjeni ehloniphekile. Lapha ku Isitolo se-SARM, sithengisa ama-SARM asezingeni eliphakeme: azanyiwe, ahlolwa, futhi akhiqizwa e-UK ngama-Bodybuilt Labs. 

 

Ingabe ama-SARM aphephile ne-FDA avunyelwe?

Kukhona ingxoxo enkulu neqhubekayo ehambisana nombuzo othi, "ingabe ama-SARM aphephile?". Ngeshwa, asikasitholi isitatimende esicacile mayelana nokuphepha noma amandla esikhathi eside alo muthi. Ngaphandle kwalokho, i-Food and Drug Administration (i-FDA) kusukela ngo-2021 ayizange ibheke ama-SAR njengento evunyelwe ukuyithatha. Ngokwengxenye enkulu, ama-SAR atholakala ukuthi angathengwa kepha kuphela ngezinjongo zocwaningo. Noma lapho kusemthethweni khona ukusebenzisa amaSARM ngezinhloso ezithile, kufanele uhlale ukukhumbula lokhu futhi uthinte uhla lwemithombo esemthethweni ukuthola umhlahlandlela. 

 

Ingabe ama-SARM asemthethweni?

Ama-SAR ayisidakamizwa esitholakalayo cishe emhlabeni wonke. E-US nase-UK, kusemthethweni ngokuphelele ukuthenga noma ukuthengisa iningi lazo. Uma noma ngubani efuna, angakwenza.

Kodwa-ke, kwamanye amazwe afana ne-Australia, ama-SARM awavulelekile wonke umuntu: kunemikhawulo. Uzokwazi ukufinyelela kuzo ngokufanele kuphela uma unencwadi kadokotela. 

 

Ngabe Udokotela Anganginika Ama-SARM?

AmaSARM kusengumuthi ophenywa yi-FDA. Ngakho-ke, ngeke kulunge ngokomthetho ukuthi udokotela wakho asikisele ukuthi ubathathe. Odokotela abagunyaziwe abakwazi ukunquma ama-SAR ngqo. Kodwa-ke, njengoba kusacutshungulwa i-FDA, uma noma yimuphi umgijimi efuna ukuvivinya umuthi ngokuzithandela, angakwenza lokho - kepha kuzodingeka abe ne-Therapeutic Use Exemption (TUE) evela e-USADA.

Lokhu ngokuvamile kunikezwa ngaphansi kwezimo eziqinile nezicacisiwe, futhi kunikeza abasebenzisi ithuba lokukhishwa ngokuhambisana ne-World Anti-Doping Agency Standards. Lokhu kungaba inqubo ende futhi kungenzeka unikezwe kuphela uma unesimo sempilo noma isimo esidinga ukusetshenziswa kwama-SARM ngokusobala. Lokho kusho, akunakwenzeka, noma uhlu belungeke lube khona. 

Mayelana nalokhu, i-USADA ithi:

"Uhlelo lokufaka isicelo se-TUE luphelele futhi lwenzelwe ukulinganisa isidingo sokuhlinzeka abagijimi ukufinyelela emithini ebucayi ngenkathi kuvikelwa amalungelo abasubathi abahlanzekile okuncintisana ezingeni elilinganayo."

Ngakho-ke, uyabona ukuthi lezi zinyathelo zikhona ukuvimbela ukudlala okungcolile noma ubungozi bezingozi zezempilo phakathi kwabagijimi, kodwa futhi zilungele ukusiza labo abazidingayo. Ngaphansi kwalezi zimo ezivunyelwe ama-SARM angasetshenziswa ngokusemthethweni njengokwelashwa. 

 

Asebenza kanjani ama-SARM?

Ama-SAR asebenza emzimbeni ngokukhomba i-androgen eyodwa yemisipha yamathambo. Ithola ama-androgen receptors avela ezingxenyeni ezihlukene zomzimba futhi asebenze kuwo ngokukhetha, ngezindlela ezifana nokukhulisa izicubu zemisipha nokuqinisa ukwakheka kwamathambo. Baxhuma amangqamuzana amathambo nezicubu zemisipha: ngakho-ke, ayasiza kumaprotheni synthesis, futhi andisa ukugcinwa kwe-nitrogen. 

 

Yiziphi izithako ze-SARM?

Izithako ziyahlukahluka kuye ngohlobo, kepha ama-SARM athengiswa kakhulu futhi anqunyiwe afaka phakathi iCardarine, i-Ostarine, iLigandrol, i-Testolone RAD-140, ne-YK-11. Ngaphandle kwalokhu, amavithamini namaminerali afakwa kuma-supplements ngokuya ngemiphumela oyifunayo. 

 

Ingabe ama-SARM angcono kune-Steroids? Ingabe ama-SARM aphephile?

Lapho ubheka impendulo yombuzo othi, "ingabe ama-SARM aphephile noma cha?", Kufanele ucabange ngokuphepha kwe-steroids futhi. Iqiniso langempela ukuthi ama-SARM angcono kune-steroids evela emibonweni yabantu abaningi njengoba imiphumela yabo emibi yezokwelapha neyomzimba ingabonakali esikhathini esifushane. Noma kunjalo, azikavunyelwa ngokomthetho. 

 

Kungani Kufanele Ngisebenzise Ama-SARM?

Ama-SAR angenye yezidakamizwa ezithandwayo ezinkulu zokukhula kwemisipha. Abasubathi nabakhi bomzimba ikakhulukazi kungenzeka ukuthi bathathe lesi sidakamizwa ukukhulisa ukusebenza kwabo. Uma u-bulking noma uthanda nje ukubonisa imisipha emikhulu, ama-SARM kungenzeka akhiqize imiphumela oyifunayo. Kodwa-ke, kufanele ukhumbule ukubuza lo mbuzo, "ngabe ama-SARM aphephile?" futhi ulinganise ukuthi ngabe kuyinketho enengqondo, esemthethweni, futhi enempilo kuwe. 

Kunezizathu eziningi ezizwakalayo zokuthi kungani ungasebenzisa ama-SARM futhi ochwepheshe bezokwelapha bangavuma ukuxoxa ngezinketho nawe noma bengakwazi ukubanikeza zona. Ngaphansi kwe-Therapeutic Use Exemption esixoxe ngayo phambilini, ezinye izimo ezivamile ukuqeda izifo zemisipha, i-osteoporosis, i-Alzheimer's, nezinkinga ze-hormone yokukhula. 

 

Ingabe kukhona ama-SARM kuma-Supplements e-Dietary?

Uma usuvele uzibuza ukuthi, "ngabe ama-SARM aphephile?", Uzofuna ukubheka ukuze uqiniseke ukuthi awuthengi noma yiziphi izinto ezibandakanya ama-SAR ngaphandle kolwazi lwakho. Ama-SAR awamukelwa ngokomthetho ukuthi asetshenziselwe izithasiselo zokudla nhlobo. Yize, ngokudabukisayo, kunezithako eziningi zokudla ezimakethe eziqukethe ama-SARM.

Lokhu kuzohlala kungekho emthethweni njalo kubhekwe njengokungcolile. Njengama-SARM, lena yimakethe enzima futhi engaba yingozi ukuyisebenzisa futhi kufanele uthenge kuphela izithako zokudla emithonjeni evunyelwe. 

 

Ngabe amaSARM Anqatshelwe yini ohlwini lweWorld Anti-Doping Agency (WADA)?

Uhlu lwe-WADA (noma iWorld Anti-Doping Agency) luqukethe amagama azo zonke izidakamizwa ezingavunyelwe zanoma yiluphi uhlobo lomuntu owenza ezemidlalo. I-ejensi ivuselela uhlu lwayo minyaka yonke futhi isebenza kusukela ngoJanuwari 1 walowo nyaka. Ngokuya ngokubuyekezwa kwakamuva kweWADA, imikhiqizo yamaSARM ayivunyelwe ukusetshenziswa kwezemidlalo ngaphansi kwemihlahlandlela yabo. Abasubathi abakwazi ukuba nalesi sidakamizwa ukukhulisa amandla abo ngaphandle kokuthi babekwe ohlwini lwabo lokukhululwa njengoba kushiwo ngaphambili. 

 

Ngabe Zikhona Izifundo Zezehlakalo Ngokusetshenziswa Kwama-SARM?

Abantu abaningi bathathe ama-SARM ngaphansi kokuhlolwa komtholampilo, njengoba benikezwe i-TUE evela e-USADA. Ezimweni eziningi, laba basebenzisi babike ulwazi lwabo lonke njengolusizo. Abaningi bathi bazimisele ukuqhubeka nokusebenzisa ama-SARM isikhathi eside uma sekuvunyelwe ezingeni elibanzi. Vele, lezi zifundo zisanda kwenzeka futhi imiphumela yesikhathi eside yalaba bahlanganyeli ayikaziwa: esikhathini esifushane, kubonakala sengathi iveze imiphumela emihle. 

 

Ingabe ama-SARMS aphephile kwabesifazane?

Manje umbuzo uthi: "ingabe ama-SARM aphephile kwabesifazane?". Ungajabula ukwazi ukuthi kuphephe ngokulinganayo kunoma imuphi umuntu omdala ukuthatha ama-SARM athile ngaphansi kwezimo ezivunyelwe, ngakho-ke abesifazane bangakwenza. Abesifazane basengozini ephindwe kane yokuhlushwa i-osteoporosis kunamadoda ngakho-ke, ngaphansi kocwaningo lwezokwelapha, lezi zithasiselo zingasiza kakhulu ekulweni namathambo aqhekekile futhi anezimbobo. Ukwakheka komzimba wemvelo kwabesifazane nakho kuvame ukwenza ukulahleka kwamafutha kube nzima ezindaweni ezithile ezifana nezinqulu nesisu. 

Kodwa-ke, izinhlobo ezahlukahlukene zama-SARM zingadala ukusabela okwehlukile, kanti amanye ama-SARM kusolwa ukuthi anemiphumela ehlukile ohlelweni lokuzala lwabesifazane kunelowesilisa. Abanye besifazane bangahle futhi bafune ukugwema izithasiselo ezilingisa kakhulu imiphumela ye-testosterone, ngokwesibonelo ukwanda kwezinwele zomzimba noma izwi eliphansi. Akunandaba nomkhiqizo, abesifazane kuzodingeka bathathe isilinganiso esincane kunabesilisa. 

Ama-SAR asebenza ngezicubu zomzimba namathambo, ngakho-ke azoba nemiphumela oyifunayo kumasipha kunoma ngubani ofuna ukukhulisa isisindo somzimba noma ukushisa amafutha omzimba. Lokho akusho ukuthi imiphumela akufanele icatshangwe. Njengoba kufanele uzibuze njalo ngombuzo othi "ngabe ama-SARM aphephile?", Kubalulekile futhi ukulandela imihlahlandlela yezomthetho futhi ukhumbule ukuthi amaSARM awavunyelwe njengamanje. Abesifazane abakhulelwe, kungenzeka ukuthi bakhulelwe, noma bancelisa akufanele uthathe ama-SAR ngaphansi kwanoma yiziphi izimo. 

 

Yimaphi ama-SARM ahamba phambili?

Ama-SAR angenza umsebenzi omningi emzimbeni wakho, futhi-ke kuya ngempilo yakho nokuthi yiziphi izinhlobo zemiphumela ofuna ukuyizuza. Uma ubuza ngama-SARM amahle kakhulu, sizoncoma i-Ostarine (MK-2866) lapho kuvunywa ngokwelashwa njengolusebenza kakhulu nolufanele nxazonke. Kulabo abafuna ukunciphisa umzimba, iLigandrol (LGD-4033) ikhiqiza imiphumela ecacile.

Lokhu futhi kuyisiphakamiso esivamile ngaphansi kwemvume yezokwelapha kwabesifazane, ngoba kugwema izimpawu eziningi ezihambisana ne-testosterone abanye besifazane abazithola zingathandeki, noma kugwema ukwandisa ezinye izinguquko zamahomoni ezenzeka empilweni yowesifazane. 

Ngaphandle kwalokho, i-Myostine YK-11 ithuthukisa amandla ne-Andarine S4 yenzelwe ukulahlekelwa isisindo samafutha.

 

Ngemininingwane engaphezulu, zizwe ukhululekile uku Xhumana nathi! Singajabula kakhulu ukuxoxa kabanzi nawe mayelana nokuthi ama-SARM aphephile yini kuwe, aphendule imibuzo yakho, futhi ahlele uhlelo olusebenzela izinhloso zakho.