Izinzuzo zama-SARM: Okufanele Ukwazi
Ama-SAR anikela ngezinzuzo ze-testosterone ngaphandle kwemiphumela emibi. AmaSARM amele ama-Selective Androgen Receptor Modulators, futhi ayisigaba esiyingqayizivele semithi eklanyelwe ukwelapha izifo ezifana nesifo i-Alzheimer's and osteoporosis.
Basiza ekwakheni isisindo semisipha futhi bakhuthaze ukwehla kwesisindo. AmaSARM aphephe impela uma esetshenziswa ngemvume, futhi awabambi iqhaza ezinkingeni zomfutho wegazi. Azinabo ubuthi futhi azibeki engcupheni yokusebenza kwesibindi. Ama-SAR angasiza futhi ekulungiseni ukulimala okunezinyanga noma ngisho neminyaka ubudala.
Ezinye izinzuzo zama-SARM zibonakala kahle - udinga kuphela ukubheka abakhi bomzimba abafunga ngabo. Noma kunjalo, akuzona nje ukulungiswa okusheshayo.
Ukuze uthole izinzuzo eziphezulu zama-SARM, udinga ukulandela umjikelezo ofanele futhi uthathe umthamo ngendlela efanele. Ama-SAR asetshenziswa ngabakhi bomzimba, abafundisa ukuqina, nalabo abafuna ukulahlekelwa ngamafutha omzimba.
Kunezinhlobo ezahlukahlukene zama-SARM atholakalayo e-UK, futhi angathengwa ku-inthanethi noma ezitolo ezikhethekile. Ama-SAR abiza kancane kune-steroids yendabuko nama-prohormones.
Hlobo luni lwama-SARM akhona?
Olunye lwezinhlobo zakamuva zama-SARM ngu I-RAD-140, eselidume kakhulu kulo lonke elase-UK. Ine-anabolic emangalisayo ku-androgenic ratio ka-90 kuye ku-1, okusho ukuthi abantu abalandela umjikelezo we-RAD-140 bazothola izinzuzo zokwanda kwemisipha ngaphandle kwemiphumela emibi yezidakamizwa ze-androgenic. I-RAD-140 ibuye ikhawulele umphumela we-testosterone, ngaleyo ndlela inciphise izinkinga ze-prostate emadodeni. Ukuze uthole imiphumela efanelekile, i-RAD-140 kufanele ithathwe kumjikelezo wamaviki ama-4 kuye kwayi-6.
Ostarine enye i-SARM eyaziwayo esetshenziswa abantu abaningi. Isetshenziselwa ukugcina isisindo semisipha noma ngesikhathi sokushoda kwama-calories. I-LGD-4033 ifana ne-Ostarine kepha inamandla amakhulu ama-12. Kukhonjisiwe njenge-ejenti enhle ye-bulking, ngokungafani ne-Ostarine, esetshenziswa kangcono kumjikelezo wokusika.
Inzuzo yale SARM ukuthi ayinayo i-steroid ngokwemvelo futhi ibophezela kuma-androgen receptors ngokukhetha kakhulu.
Lokhu kunikeza ukulawula okukhulu kulokhu kunama-steroids: ama-anabolic steroids abopha cishe kunoma iyiphi iseli, futhi ezimweni eziningi kuveza imiphumela engafuneki noma eyingozi. Ukukubeka kalula, awekho amandla wokukhetha ukuthi ama-steroids abopha imisipha yakho futhi akhuthaze ukukhula, noma aphazamise umsebenzi wezitho ezibalulekile njengenhliziyo nesibindi sakho.
Ngemuva kokubopha, i-LGD-4033 idala umphumela we-anabolic emisipheni nasemathanjeni, okusiza ekukhuleni nasekuqiniseni lezi zicubu. Ukusebenzisa i-LGD-4033 kusho ukuthi abasebenzisi baphephile emiphumeleni ejwayelekile eyingozi ye-steroids yendabuko - okungahle kube nomphumela wezinkinga zokubala, izinduna nezindlala.
I-MK-677, noma i-Ibutamoren, uhlobo lwe-SARM olungeyona i-peptidic - engaqukethe ama-peptide - ngokwemvelo. Ithathwa ngomlomo futhi iyasiza ekwandeni kwemisipha nobukhulu bamathambo.
Izithasiselo ezinjengalezi zikhuthaza ukukhula kusetshenziswa i-Insulin-like Growth Factor 1, eyaziwa nangokuthi yi-IGF-1. Le yihomoni elingisa ezinye zezici ze-insulin (kepha ngokwamakhemikhali ayifani, ngakho-ke akufanele isetshenziswe esikhundleni sayo). I-IGF-1 ikhona emzimbeni ngokwemvelo, futhi idlala indima ebalulekile ekukhuleni kwengane nasekuthombaneni. Kubantu abadala amanani emvelo mancane kakhulu, ngakho-ke ukuwengezela kungaba nemiphumela ye-anabolic.
Izinzuzo zama-SARM ekulaleni
AmaSARM abangela ukukhishwa okuphezulu kwe-IGF-1 emzimbeni asetshenziswa phakathi kwabantu abadala abanokukhula noma ukushoda kwamahomoni. Njenganoma yini ekhulisa imisipha, impela ziyaziwa nasemphakathini wokwakha umzimba.
Ukudla kwansuku zonke kwe-25mg ye-MK-677 kungakhuphula amazinga e-IGF-1 ngama-60% esikhathini esingamaviki ayisithupha. Lokhu kungaphezulu kakhulu kwesilinganiso semvelo esibonwa kubantu abadala: eceleni kokudla okunempilo, okunothe ngamaprotheni, nezinye izindlela ezinempilo njengokulala okuhle nokugwema ukubhema notshwala, kungenzeka ukuthi abasebenzisi bakhe imisipha ukudlula amandla abo amanje nomzimba osikiwe amafutha.
I-MK-677 ayiyona i-hormonal, futhi imiphumela emihle iyatholakala lapho ithathwa ngomjikelezo wezinyanga ezintathu. Isikhathi esihle sokuthatha iMK-3 kusebusuku, ngaphambi nje kokulala. Kuzokusiza nokuthi ulale ngokushesha, ngenxa yokuba khona kwekhemikhali ebizwa nge-ghrelin.
IGhrelin ikhona ngokwemvelo emzimbeni futhi ibhekene nesigqi sakho se-circadian, esitshela umzimba ukuthi kufanele ulale nini nokuthi uvuke nini. Labo abakuthola kunzima ukulala bayayazi imithelela okuba nayo empilweni yansuku zonke, futhi ikakhulukazi enkambisweni yokuzivocavoca umzimba. Lapha, izinzuzo zamaSARM zingaba zinkulu. Akumnandi futhi akuphephile ukuphakamisa izinsimbi ngenkathi ulele nje!
Abasebenzisi abaningi bathola ukuthi i-MK-677 inemiphumela emihle kakhulu kubo bobabili ikhwalithi yabo yokulala nesikhathi sokulala, kanye nemizwa yokuthi "baphumule" futhi banciphise isidingo sokuvuka ebusuku. Ngenkathi kungafanele bathathwe ngemiphumela yabo yokulala bodwa, kuyinzuzo emangalisayo yama-SARM.
Abantu abazuza kakhulu ekusetshenzisweni kwama-SARM babahlanganisa nokudla okunempilo nokuvivinya umzimba njalo. Qaphela ukuthi akuyona into yokulungisa imilingo: ukuhlala phambi kwekhompyutha amahora amaningi noma ukudla amakhukhi amakhulu kashokoledi ngeke kukusize ukunciphisa ngisho noma uthatha ama-SARM ukunciphisa isisindo sakho! Uma ukhetha inqubo efanelekile futhi uhlala uphephile futhi ukhuthazekile, ama-SARM azokusiza ukuthi ufeze imiphumela oyifunayo ngokushesha.
Izinzuzo zama-SARM esikhunjeni
Kungenzeka wake wezwa izithasiselo ezifana neMK-677 (Ibutamoren) ebizwa ngokuthi “umthombo wobusha”! Lokhu kungenxa yomphumela wazo emazingeni e-collagen emzimbeni. I-Collagen ibhekele ukuqina kwesikhumba nezinwele, futhi imikhiqizo yama-collagen efana nokhilimu wamehlo imakethe yonke ukuqinisa isikhumba esivulekile nokunciphisa ukubonakala kwemibuthano emnyama, imibimbi nezikhwama zamehlo. Izinga eliphakeme le-collagen lidala isikhumba esiqinile, esibushelelezi nesibukeka kancane uma sengezwa njalo.
Lezi zithasiselo azikhulisi kuphela ukukhiqizwa kwe-collagen emzimbeni, kodwa futhi zinciphisa ukwehla kwayo. Lokhu kusho nokuthi ukulimala okudala, okunenkani kungasizakala ngokwanda kwe-collagen, kanye namanxeba okuhola kanye nobunzima bemisipha endleleni eya ekululameni.
Izinzuzo zamaSARM engqondweni
UGhrelin, i-hormone esikhulume ngayo ngekhwalithi yokulala, futhi ungumdlali ophambili ekusebenzeni kobuchopho kwansuku zonke. IGhrelin ikhona kuma-SARM amaningi afana neMK-677 (Ibutamoren) futhi inomthelela omkhulu ezindaweni ezinjengememori, ukugqugquzela, nobuciko ebuchosheni.
Ungathola ukuthi lokhu kuhambisana nokulala kwakho nokuqina komzimba: lapho uphumule ngokwengeziwe, uzokwenza kangcono empilweni yakho yansuku zonke nangesikhathi sokuzivocavoca. Ukuzivocavoca umzimba kungcono, uzolala kangcono! Lo umjikelezo wokuthi "ube ndawonye" okunzima ukuwulungisa lapho abagijimi begijima ngamandla amancane.
“Inkungu yobuchopho” kuyiphupho elibi lapho kuziwa ekubeni namandla okuzivocavoca umzimba, ukuvuka ekuseni kakhulu, noma ukwenqabe ekudleni okungenamsoco okuthandayo. Njengoba ilula njengemisindo ye-ghrelin, ubuchopho obusebenzayo bunamandla okuphula lo mjikelezo futhi bugcine amehlo abantu abathanda ukuqina emklomelweni.
Lokhu kungenye yezinzuzo zama-SARM angahle abonakale emancane ekuboneni kuqala, kepha anomunye wemiphumela emide kakhulu yesikhathi eside noma ngaphandle kwesidingo sokugoba noma ukwenza umnqamulajuqu wesisindo. Ukugcina ingqondo ephilile futhi ephumule kubaluleke kakhulu lapho ulandela inqubo eqinile yokuqina, futhi ukuhlala uphilile engqondweni kuzokwenza ukuthi unamathele ezinhlosweni zakho.
Zisebenza Kanjani?
Kunesidingo esikhulu samaSARM. Ngenxa yezakhiwo zabo zokwakha imisipha kanye nokuchitheka kwamafutha, bavame ukufakwa kwizengezo ezithengiswa kubantu abathanda ukuqina. I-testosterone engapheli, ethinta amazinga e-cholesterol nokusebenza kwesibindi okushintshiwe (umphumela ovamile futhi oyingozi wokusetshenziswa kwe-steroid) kungancishiswa zombili ngezinzuzo zama-SARM.
Eminyakeni yamuva nje, amaSARM abelokhu ekhula emhlabeni wonke njengomkhiqizo osemthethweni; emazweni amaningi kulula ukuthenga nokuthengisa. Kodwa-ke, ngaphansi kwemithetho eminingi, ayatholakala ukuthi angathengwa ngezinhloso zocwaningo kuphela.
Lokhu kunjalo emthethweni wase-UK nowe-USA, ngaphandle kwalapho kunqunywe ngokusemthethweni nguchwepheshe noma ngaphansi kokukhululwa kwezokwelapha. Ama-SARM amaningi ngenxa yalokho abhalwe emaphaketheni awo njengamakhemikhali ocwaningo noma "hhayi ukusetshenziswa" futhi kufanele alandelwe ngokufanele. Eminye imikhiqizo yama-SARM engavunyelwe ukusetshenziswa nayo ifakwa kumaphilisi futhi ithengiswa njengezithako zokudla: lokhu futhi akusikho ukusetshenziswa okuvumelekile.
Lokho kusho, kuya ngemithetho lapho ukhona - abanye ochwepheshe bezokwelapha bayakwazi ukunquma ama-SAR, futhi uma uhlala endaweni ethile lapho bevumeleke khona ukusetshenziswa kwezokwelapha, vakashela nje esitolo semithi noma sezokwelapha. Lapha, uzokwazi ukuthola ama-SARMS ahlonishwa kakhulu athengiswayo afana nezidingo zakho.
Kungakhathaliseki ukuthi uyakwazi ukufinyelela ezikhungweni ezinjengalezi, kuhlale kubalulekile ukusebenzisa imithombo ehloniphekile yezithasiselo zokwengeza imisipha. Lapha ku Isitolo se-SARM, sizama, sihlole, futhi senze yonke imikhiqizo yethu e-UK ngaphansi kwamaLebhu Wokwakha.
Ama-steroid vs. Ama-SARM
Ama-steroid asetshenziselwa ukuzuza kwemisipha, kodwa izindleko zawo ziyingozi. Ama-steroid athumela inqwaba yemiyalezo exubile kuma-receptors emzimbeni wakho futhi adidanise ubuchopho. Lokhu kusho ukuthi kungalimaza noma yisiphi isitho: izinkinga zingazuma futhi kube nzima ukubikezela.
Ama-steroid asemthethweni emazweni ambalwa, njenge: Canada, Iran, Mexico, Panama, Greece, Poland, Ukraine, India, Pakistan, nase Japan.
Ama-SAR nama-steroids acishe afane, kepha awafani. Kukhona umehluko omncane kodwa obalulekile phakathi kwabo:
Ama-SAR ayisona isimangaliso futhi, ngenkathi evikela imiphumela emibi eminingi ye-steroids, ambalwa angahlala. Kunezinzuzo eziningi zama-SARM; ziyaziwa ukuthi ziphephe kune-steroids, kepha njalo kufanele kukhunjulwe ukuthi akukho lutho olungamaphesenti ayikhulu olumsulwa. Kokubili ama-steroids nama-SARM anokuphazamiseka kwawo futhi kufanele kusetshenziswe njalo ngokomthetho futhi kucwaningwe ngokuphelele ngaphambi kokusetshenziswa.
Uma ufuna ezinye izizathu zokuthi kungani ama-SAR eyindlela engenabungozi kangako, cabanga ukuthi ama-steroids kanye nokuba khona okwandisiwe kwe-testosterone kuzo kungadala ukulahleka kwezinwele nokukhula kwamabele emadodeni. Kungadala izinduna zomzimba nezinkinga zentukuthelo, kanye nemiphumela eyingozi yesikhathi eside efana nobuthi besibindi. Ngokungafani ne-steroids, ama-SARM asebenza ngomlomo futhi awadingi imijovo.
Ama-SAR awona ama-anabolic steroids; zinganekwane zokwenziwa ezibopha kuma-androgen receptors. Ngokuya ngesakhiwo sabo samakhemikhali, basebenza njengama-agonists agcwele noma abaphikisi. Ekugcineni, kufakazelwe ukuthi izinzuzo zama-SARM kanye nemiphumela engaba khona kukhethwa kuma-anabolic steroids.
Ukukhathazeka ngokuqothulwa kokuduma kwamaSARM
Ama-SAR awakavunyelwa yi-FDA (i-US Food and Drug Administration) futhi ngenxa yalokho ahlotshaniswa nokukhathazeka okukhulu kwezokuphepha. Bangakhuphula ubungozi bokuhlaselwa yisifo senhliziyo kanye nezinkinga ezisongela impilo noma zokuguqula izinkinga njengokulimala kwesibindi.
Ngenkathi iyingozi kangako kune-steroids ngezinjongo zokuthola ezokwelapha noma zemisipha, izifundo ezisebenzayo zisemisha futhi imiphumela yesikhathi eside yokusetshenziswa kwamaSARM ejwayelekile ayaziwa. Kuze kube yilapho ukuhlolwa kwezokwelapha nocwaningo kukhombisa ukuthi zikulungele ukusetshenziswa ngaphandle kokukhathazeka, akufanele ufiphazwe izinzuzo zama-SARM.
AmaSARM awekho emthethweni ukusetshenziswa okungagunyaziwe ezindaweni eziningi futhi njengazo zonke izinto ezingagunyaziwe zinamandla okuba yingozi, ngakho-ke qaphela imiphumela yazo emibi futhi uhlale ufuna ukuholwa nguchwepheshe uma ufuna ukwazi ukuzisebenzisa.
Akufanele nangaphansi kwanoma yiziphi izimo ukuthi abasebenzisi bakhulise isilinganiso sabo njengoba ukweqisa ngokweqile kungaba nemiphumela eyingozi kakhulu. Abasebenzisi kufanele futhi bafune iseluleko sezokwelapha ngaphambi kokuphuma ngokuphelele kuma-SARM njengoba indlela "ebandayo ye-turkey" nayo ingaba yingozi.
Ingabe ama-SARM aphephile ukusetshenziswa?
AmaSARM aziwa kabanzi njengomuthi ophephile kune-anabolic steroids. Abantu abaningi bafuna ukwakha imisipha yabo ngendlela yemvelo ngaphandle kwemiphumela emibi ye-steroids; kulezi zimo ama-SAR angaba yisixazululo.
Olunye ucwaningo lukhombisa ukuthi ama-SARM angahle athuthukise amazinga e-cholesterol kanye nokukwazi kwabo ukukhulisa ukushuba kwamathambo. Uma ubhekene nezinkinga zokwakha umzimba, zingaba yimpendulo.
Ezinye izinzuzo zama-SARM zifaka:
- Ukushisa amafutha kukaphethiloli - kuholela ekunciphiseni isisindo kanye "nokugaya":
- Ingathuthukisa ukusebenza kokusebenza - isivinini esikhuphukile nokuqina;
- Isikhathi esinciphile sokululama kwezemidlalo;
- Isiza ukwakha isisindo somzimba esinciphile;
- Ingakhuphula amandla wethambo nokuqina kwabantu.
Okuqine kakhulu kuma-SARM
Uma uzimisele ngokuthuthukisa isimo sakho somzimba, ukucabanga ngosizo lwama-SAR uma kuvunyelwe kunamandla okuguqula isimo sakho sokuqina. AmaSARM asebenza ngokumangazayo ekwakheni amanoni amaningi nokugaya. Njengoba kushiwo ngaphambili, zingakusiza ukuthi ululame ngokushesha okukhulu ekulimaleni: ngenkathi kungafanele uziphushe ngaphambi kokuthi ulungele, kungakhathaza ukuhlala ulinde, futhi ukulimala okulandelayo kuzonciphisa inqubo kakhulu. Ukuzizwa unamandla ngemuva kokubuyela emuva kuletha ukuzethemba kokubuyela ezinyaweni zakho ngokushesha kunangaphambili.
Ngeminye imininingwane, zizwe ukhululekile Xhumana nathi! Singajabula kakhulu ukuxoxa nawe ngemibuzo yakho yokufaneleka, noma senze uhlelo olusebenzela indlela ophila ngayo nezinhloso zakho.